Shweta Motiwala, MD, MPH | Advanced Heart Failure Comprehensive Care Center

Assoc. Clinical Professor

M_MED-CORE-CARD

Affiliation

I am an Advanced Heart Failure and Transplant cardiologist, and the Director of Heart Failure Disease Management at UCSF. I have clinical expertise in evaluating and treating patients across the spectrum of heart failure disease severity, including those who require mechanical circulatory support or heart transplantation. I have a particular interest in developing chronic disease management programs to improve clinical outcomes and quality of life in patients with heart failure. These include initiatives to expand the use of remote monitoring technologies and platforms, to optimize the application of guideline-directed medical and device therapy, and to improve access to care and transitions of care.

My research interests include the use of biomarkers in understanding response to therapy and outcomes in heart failure, evaluation of novel remote monitoring and therapeutic devices, and approaches to improving delivery of care to broad patient populations.

Publications

Care of Adult Heart Transplant Recipients by the Primary Care Provider: A Practical Roadmap.

Journal of clinical medicine

Wu Y, Gao L, Lazo J, Martinez B, Grewal S, Yurkova I, Galeota J, Nash C, Cutler M, Tarango N, Prasad P, Cheng R, Motiwala S, De Marco T

2024 ACC Expert Consensus Decision Pathway for Treatment of Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversight Committee.

Journal of the American College of Cardiology

Maddox TM, Januzzi JL, Allen LA, Breathett K, Brouse S, Butler J, Davis LL, Fonarow GC, Ibrahim NE, Lindenfeld J, Masoudi FA, Motiwala SR, Oliveros E, Walsh MN, Wasserman A, Yancy CW, Youmans QR

Risk Stratification in Advanced Heart Failure: Can Simple Hemodynamic Indices Replace Comprehensive CPET?

JACC. Heart failure

Motiwala SR, Nayor M

Induction immunosuppression and post-transplant diabetes mellitus: a propensity-matched cohort study.

Frontiers in endocrinology

Gupta SK, Mostofsky E, Motiwala SR, Hage A, Mittleman MA

Outcomes With Peripheral Venoarterial Extracorporeal Membrane Oxygenation for Suspected Acute Myocarditis: 10-Year Experience From the Extracorporeal Life Support Organization Registry.

Circulation. Heart failure

Nunez JI, Grandin EW, Reyes-Castro T, Sabe M, Quintero P, Motiwala S, Fleming LM, Sriwattanakomen R, Ho JE, Kennedy K, Tonna JE, Garan AR

Cardiogenic shock related cardiovascular disease mortality trends in US population: Heart failure vs. acute myocardial infarction as contributing causes.

International journal of cardiology

Ghajar A, Ordonez CP, Philips B, Pinzon PQ, Fleming LM, Motiwala SR, Sriwattanakomen R, Ho JE, Grandin EW, Sabe M, Garan AR

Post-transplant mortality and graft failure after induction immunosuppression among Black heart transplant recipients in the United States.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Salia S, Mostofsky E, Gupta S, Lehman L, Barrera FJ, Liou L, Motiwala SR, Mittleman MA

2021 Update to the 2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Solution Set Oversig

Journal of the American College of Cardiology

Writing Committee, Maddox TM, Januzzi JL, Allen LA, Breathett K, Butler J, Davis LL, Fonarow GC, Ibrahim NE, Lindenfeld J, Masoudi FA, Motiwala SR, Oliveros E, Patterson JH, Walsh MN, Wasserman A, Yancy CW, Youmans QR

From Proteomics to Therapeutics: Sex Differences in Cardiovascular Disease Risk Do Matter.

Journal of the American College of Cardiology

Motiwala SR

A clinical and proteomics approach to predict the presence of obstructive peripheral arterial disease: From the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) Study.

Clinical cardiology

McCarthy CP, Ibrahim NE, van Kimmenade RRJ, Gaggin HK, Simon ML, Gandhi P, Kelly N, Motiwala SR, Mukai R, Magaret CA, Barnes G, Rhyne RF, Garasic JM, Januzzi JL

Single-Molecule Counting of High-Sensitivity Troponin I in Patients Referred for Diagnostic Angiography: Results From the CASABLANCA (Catheter Sampled Blood Archive in Cardiovascular Diseases) Study.

Journal of the American Heart Association

McCarthy CP, Ibrahim NE, Lyass A, Li Y, Gaggin HK, Simon ML, Mukai R, Gandhi P, Kelly N, Motiwala SR, van Kimmenade RRJ, Massaro JM, D'Agostino RB, Januzzi JL

Predicting new-onset HF in patients undergoing coronary or peripheral angiography: results from the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA) study.

ESC heart failure

Ibrahim NE, Lyass A, Gaggin HK, Liu Y, van Kimmenade RRJ, Motiwala SR, Kelly NP, Gandhi PU, Simon ML, Belcher AM, Harisiades JE, Massaro JM, D'Agostino RB, Januzzi JL

2017 ACC Expert Consensus Decision Pathway for Optimization of Heart Failure Treatment: Answers to 10 Pivotal Issues About Heart Failure With Reduced Ejection Fraction: A Report of the American College of Cardiology Task Force on Expert Consensus Decisi

Journal of the American College of Cardiology

Yancy CW, Januzzi JL, Allen LA, Butler J, Davis LL, Fonarow GC, Ibrahim NE, Jessup M, Lindenfeld J, Maddox TM, Masoudi FA, Motiwala SR, Patterson JH, Walsh MN, Wasserman A

Systematic Evaluation of Endothelin 1 Measurement Relative to Traditional and Modern Biomarkers for Clinical Assessment and Prognosis in Patients With Chronic Systolic Heart Failure: Serial Measurement and Multimarker Testing.

American journal of clinical pathology

Gaggin HK, Truong QA, Gandhi PU, Motiwala SR, Belcher AM, Weiner RB, Baggish AL, Januzzi JL

Usefulness of Multiple Biomarkers for Predicting Incident Major Adverse Cardiac Events in Patients Who Underwent Diagnostic Coronary Angiography (from the Catheter Sampled Blood Archive in Cardiovascular Diseases [CASABLANCA] Study).

The American journal of cardiology

McCarthy CP, van Kimmenade RRJ, Gaggin HK, Simon ML, Ibrahim NE, Gandhi P, Kelly N, Motiwala SR, Belcher AM, Harisiades J, Magaret CA, Rhyne RF, Januzzi JL

Associations Between Psychological Constructs and Cardiac Biomarkers After Acute Coronary Syndrome.

Psychosomatic medicine

Celano CM, Beale EE, Beach SR, Belcher AM, Suarez L, Motiwala SR, Gandhi PU, Gaggin H, Januzzi JL, Healy BC, Huffman JC

A Clinical and Biomarker Scoring System to Predict the Presence of Obstructive Coronary Artery Disease.

Journal of the American College of Cardiology

Ibrahim NE, Januzzi JL, Magaret CA, Gaggin HK, Rhyne RF, Gandhi PU, Kelly N, Simon ML, Motiwala SR, Belcher AM, van Kimmenade RRJ

Native T1 value in the remote myocardium is independently associated with left ventricular dysfunction in patients with prior myocardial infarction.

Journal of magnetic resonance imaging : JMRI

Nakamori S, Alakbarli J, Bellm S, Motiwala SR, Addae G, Manning WJ, Nezafat R

Incident Type 2 Myocardial Infarction in a Cohort of Patients Undergoing Coronary or Peripheral Arterial Angiography.

Circulation

Gaggin HK, Liu Y, Lyass A, van Kimmenade RR, Motiwala SR, Kelly NP, Mallick A, Gandhi PU, Ibrahim NE, Simon ML, Bhardwaj A, Belcher AM, Harisiades JE, Massaro JM, D'Agostino RB, Januzzi JL

Biomarkers to Predict Reverse Remodeling and Myocardial Recovery in Heart Failure.

Current heart failure reports

Motiwala SR, Gaggin HK

Effects of Optimism and Gratitude on Physical Activity, Biomarkers, and Readmissions After an Acute Coronary Syndrome: The Gratitude Research in Acute Coronary Events Study.

Circulation. Cardiovascular quality and outcomes

Huffman JC, Beale EE, Celano CM, Beach SR, Belcher AM, Moore SV, Suarez L, Motiwala SR, Gandhi PU, Gaggin HK, Januzzi JL

Design and baseline data from the Gratitude Research in Acute Coronary Events (GRACE) study.

Contemporary clinical trials

Huffman JC, Beale EE, Beach SR, Celano CM, Belcher AM, Moore SV, Suarez L, Gandhi PU, Motiwala SR, Gaggin H, Januzzi JL

Assessment of mitral valve disease: a review of imaging modalities.

Current treatment options in cardiovascular medicine

Motiwala SR, Delling FN

Concentrations of highly sensitive cardiac troponin-I predict poor cardiovascular outcomes and adverse remodeling in chronic heart failure.

Journal of cardiovascular translational research

Motiwala SR, Gaggin HK, Gandhi PU, Belcher A, Weiner RB, Baggish AL, Szymonifka J, Januzzi JL

Comparison between admission natriuretic peptides, NGAL and sST2 testing for the prediction of worsening renal function in patients with acutely decompensated heart failure.

Clinical chemistry and laboratory medicine

De Berardinis B, Gaggin HK, Magrini L, Belcher A, Zancla B, Femia A, Simon M, Motiwala S, Bhardwaj A, Parry BA, Nagurney JT, Coudriou C, Legrand M, Sadoune M, Di Somma S, Januzzi JL, Global Research on Acute Conditions Team (GREAT)

Galectin-3 and mineralocorticoid receptor antagonist use in patients with chronic heart failure due to left ventricular systolic dysfunction.

American heart journal

Gandhi PU, Motiwala SR, Belcher AM, Gaggin HK, Weiner RB, Baggish AL, Fiuzat M, Brunner-La Rocca HP, Januzzi JL

Evidence of uncoupling between renal dysfunction and injury in cardiorenal syndrome: insights from the BIONICS study.

PloS one

Legrand M, De Berardinis B, Gaggin HK, Magrini L, Belcher A, Zancla B, Femia A, Simon M, Motiwala S, Sambhare R, Di Somma S, Mebazaa A, Vaidya VS, Januzzi JL, Global Research on Acute Conditions Team (GREAT)

ST2 pathogenetic profile in ambulatory heart failure patients.

Journal of Cardiac Failure

Bayes-Genis A, Januzzi JL, Gaggin HK, de Antonio M, Motiwala SR, Zamora E, Galán A, Domingo M, Urrutia A, Lupón J

Characterization and prediction of adverse events from intensive chronic heart failure management and effect on quality of life: results from the pro-B-type natriuretic peptide outpatient-tailored chronic heart failure therapy (PROTECT) study.

Journal of Cardiac Failure

Gandhi PU, Szymonifka J, Motiwala SR, Belcher AM, Januzzi JL, Gaggin HK

Prognostic usefulness of insulin-like growth factor-binding protein 7 in heart failure with reduced ejection fraction: a novel biomarker of myocardial diastolic function?

The American journal of cardiology

Gandhi PU, Gaggin HK, Sheftel AD, Belcher AM, Weiner RB, Baggish AL, Motiwala SR, Liu PP, Januzzi JL

Head-to-head comparison of serial soluble ST2, growth differentiation factor-15, and highly-sensitive troponin T measurements in patients with chronic heart failure.

JACC. Heart failure

Gaggin HK, Szymonifka J, Bhardwaj A, Belcher A, De Berardinis B, Motiwala S, Wang TJ, Januzzi JL

Serial measurement of galectin-3 in patients with chronic heart failure: results from the ProBNP Outpatient Tailored Chronic Heart Failure Therapy (PROTECT) study.

European journal of heart failure

Motiwala SR, Szymonifka J, Belcher A, Weiner RB, Baggish AL, Sluss P, Gaggin HK, Bhardwaj A, Januzzi JL