Jason Smith, MD

Professor of Clinical Surgery
Surgery
+1 415 353-1606

Dr. Jason W. Smith is a cardiac and transplant surgeon who specializes in heart transplantation and the use of mechanical circulatory support, such as artificial heart pumps and left ventricular assist devices. He has expertise in complex cardiac procedures that include mitral valve repair and replacement, aortic valve surgery, transcatheter aortic valve procedures (minimally invasive techniques to replace a failing valve), surgeries to treat the ascending aorta and aortic arch, treatment of endocarditis (infections of the heart's inner lining), operations to correct atrial fibrillation (irregular and often rapid heartbeats), and sternal repair and reconstruction. He also manages extracorporeal membrane oxygenation (ECMO), which supports the heart and lungs by using a machine to oxygenate blood outside of the body. He is the surgical director of UCSF's heart transplantation and mechanical circulatory support programs.

Smith has been active in a national effort to increase access to heart transplantation by improving the use of donor organs. He served as a primary investigator for a nationwide clinical trial on donation after cardiac death.

Smith earned his medical degree from the Stritch School of Medicine at Loyola University Chicago, then completed a residency in general surgery and a fellowship in cardiothoracic surgery at Loyola University Medical Center. He completed a fellowship in heart and lung transplantation at Stanford Medicine. Upon completing his training, he joined the surgical faculty at the University of Washington. Prior to joining UCSF, he served as surgical director of transplant and mechanical circulatory support at the University of Wisconsin – Madison.

Smith serves on the membership and professional standards committee of the national Organ Procurement and Transplantation Network. He frequently makes presentations on issues related to organ transplantation and utilization and belongs to numerous professional and honorary societies. He is a San Francisco native.

Publications: 

Beyond Glasgow Coma Scale: Prehospital prediction of traumatic brain injury.

Surgery

Schucht JE, Rakhit S, Smith MC, Han JH, Brown JB, Grigorian A, Gondek SP, Smith JW, Patel MB, Maiga AW

Structural racism: A concept analysis.

Nursing outlook

Smith JW, Mayo A

Distance to Burn Center Does Not Impact Long-term Anxiety and Depression Risk Following Burn Injury.

Journal of burn care & research : official publication of the American Burn Association

Risinger WB, Dye CN, Thompson SK, Uma CV, Keeven DD, Nash NA, Smith JW, Bozeman MC

Six Square Miles of Urban America: Association Between Firearm Discharge, Injury, and Fatality.

Journal of the American College of Surgeons

Risinger WB, Uma CV, Benns MV, Ruther MH, Nash NA, Bozeman MC, Coleman JJ, Smith JW, Harbrecht BG, Miller KR

Phase I clinical trial of the feasibility and safety of direct peritoneal resuscitation in liver transplantation.

American journal of surgery

Rodriguez IE, Asher ZP, Klingenberg K, Wright FL, Nydam TL, Adams MA, Bababekov YJ, Peltz E, Smith JW, Saben JL, Kennealey P, Pomposelli JJ, Pomfret EA, Moore HB

Coagulopathy in Penetrating Ballistic Cranial Trauma: A 7-Year Experience.

Neurosurgery

Alhourani A, Stephenson TL, Bridwell EM, Danehower SE, Walek KW, Smith JW, Sieg E

2024 EAST Presidential Address: One Day.

The journal of trauma and acute care surgery

Smith JW

Not So Vats: How Early Is Too Early in the Operative Management of Patients with Traumatic Hemothorax?

The American surgeon

Uma CV, Risinger WB, Nath S, Pera SJ, Smith JW

Applying the antecedent, behaviour, and consequence taxonomy to unintentional firearm injury as determined by a collaborative firearm injury database.

Injury prevention : journal of the International Society for Child and Adolescent Injury Prevention

Risinger WB, Nickols AK, Harris AN, Benns MV, Nash NA, Bozeman MC, Pera SJ, Coleman JC, Franklin GA, Smith JW, Harbrecht BG, Miller KR

Increasing Utilization of Extended Criteria Donor Hearts for Transplantation: The OCS Heart EXPAND Trial.

JACC. Heart failure

Schroder JN, Patel CB, DeVore AD, Casalinova S, Koomalsingh KJ, Shah AS, Anyanwu AC, D'Alessandro DA, Mudy K, Sun B, Strueber M, Khaghani A, Shudo Y, Esmailian F, Liao K, Pagani FD, Silvestry S, Wang IW, Salerno CT, Absi TS, Madsen JC, Mancini D, Fiedler AG, Milano CA, Smith JW

A Decade of Analysis of Unplanned Extubation Etiology in Trauma Patients Including the Impact of the COVID Pandemic.

Respiratory care

Harbrecht BG, Miller KR, Egger ME, Nash NA, Doan R, Georgel J, Franklin GA, Smith JW, Bozeman MC, Benns MV

Expanding the Donation After Circulatory Death Transplant Pool in the United States.

The Annals of thoracic surgery

Fiedler A, Miller PN, Smith JW

Plasma resuscitation improves and restores intestinal microcirculatory physiology following haemorrhagic shock.

Vox sanguinis

Schucht JE, Harbrecht BG, Bond LM, Risinger WB, Matheson PJ, Smith JW

Damage control surgery in emergency general surgery: What you need to know.

The journal of trauma and acute care surgery

Risinger WB, Smith JW

Establishing a core outcome set for blunt cerebrovascular injury: an EAST modified Delphi method consensus study.

Trauma surgery & acute care open

Ziesmann M, Byerly S, Yeh DD, Boltz M, Gelbard R, Haut ER, Smith JW, Stein DM, Zarzaur BL, Bensard DD, Biffl WL, Boyd A, Brommeland T, Cothren Burlew C, Fabian T, Lauerman M, Leichtle S, Moore EE, Timmons S, Vogt K, Nahmias J

Transplantation Outcomes with Donor Hearts after Circulatory Death.

The New England journal of medicine

Schroder JN, Patel CB, DeVore AD, Bryner BS, Casalinova S, Shah A, Smith JW, Fiedler AG, Daneshmand M, Silvestry S, Geirsson A, Pretorius V, Joyce DL, Um JY, Esmailian F, Takeda K, Mudy K, Shudo Y, Salerno CT, Pham SM, Goldstein DJ, Philpott J, Dunning J, Lozonschi L, Couper GS, Mallidi HR, Givertz MM, Pham DT, Shaffer AW, Kai M, Quader MA, Absi T, Attia TS, Shukrallah B, Sun BC, Farr M, Mehra MR, Madsen JC, Milano CA, D'Alessandro DA

Comment on: Detection and management of HLA sensitization in candidates for adult heart transplantation.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Fiedler AG, Klein L, DeMarco T, Kouretas P, Smith JW

Establishing a core outcomes set for massive transfusion: An Eastern Association for the Surgery of Trauma modified Delphi method consensus study.

The journal of trauma and acute care surgery

Gelbard RB, Nahmias J, Byerly S, Ziesmann M, Stein D, Haut ER, Smith JW, Boltz M, Zarzaur B, Callum J, Cotton BA, Cripps M, Gunter OL, Holcomb JB, Kerby J, Kornblith LZ, Moore EE, Riojas CM, Schreiber M, Sperry JL, Yeh DD

Molecules, Machines, and the Perfusate Milieu: Organ Preservation and Emerging Concepts for Heart Transplant.

Innovations (Philadelphia, Pa.)

Wisneski A, Smith JW, Nguyen TC, Fiedler AG

Effect of Plasma Resuscitation with Adjunctive Peritoneal Resuscitation on Hepatic Blood Flow and End-Organ Damage after Hemorrhagic Shock.

Journal of the American College of Surgeons

Smith JW, Schucht JE, Harbrecht BG, Bond LM, Matheson PJ

Direct Peritoneal Resuscitation for Trauma.

Advances in surgery

Pera SJ, Schucht J, Smith JW

A new pandemic and an old epidemic: The impact of COVID-19 and gun violence as measured by years of potential life lost in a US city.

Surgery

Risinger WB, Pera SJ, Bhutiani N, Ruther M, Harbrecht BG, Smith JW, Benns MV, Miller KR

Unconventional use of total artificial heart in a patient with severe, destructive prosthetic valve endocarditis.

Journal of cardiac surgery

Johnstad C, Bomareddi S, Hermsen JL, Smith JW, Fiedler AG

Survival after orthotopic heart transplantation in patients with BMI > = 35 with and without diabetes.

Clinical transplantation

Fiedler AG, Stalter L, Marka N, Dhingra R, Hermsen JL, Smith JW

Left ventricular assist device implantation by bi-thoracotomy technique: A single-center perspective.

Journal of cardiac surgery

Stoeckl EM, Smith JW, Dhingra R, Fiedler AG

Risk factors and outcomes for delayed kidney graft function in simultaneous heart and kidney transplant recipients: A UNOS/OPTN database analysis.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Parajuli S, Karim AS, Muth BL, Leverson GE, Yang Q, Dhingra R, Smith JW, Foley DP, Mandelbrot DA

Successful heart transplantation in a patient who recovered from COVID-19.

Journal of cardiac surgery

Johnstad CM, Murray D, Dhingra R, Smith JW, Fiedler AG

Orthotopic Heart Transplant: How I Teach It.

The Annals of thoracic surgery

Fiedler AG, Hermsen JL, Bommareddi S, Smith JW

Amiodarone Use Prior to Cardiac Transplant Impacts Early Post-Transplant Survival.

Cardiovascular drugs and therapy

Allana SS, Rajput FA, Smith JW, Lozonschi L, Liou JI, Johnson M, Kohmoto T, Dhingra R

2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists: A Report of the ACC Competency Management Committee.

Journal of Cardiac Failure

Writing Committee Members, Yancy CW, Drazner MH, Coffin ST, Cornwell W, Desai S, Erwin JP, Ginwalla M, Harshaw-Ellis KS, Horwich T, Kittleson M, Lala A, Lewsey SC, Marine JE, Martin C, Meehan K, Morrow DA, Schlendorf K, Smith JW, Stevens GR, ACC Competency Management Committee, Arrighi JA, Mendes LA, Adams JE, Brush JE, Dec GW, Denktas A, Fernandes S, Freeman R, Francis SA, Hahn RT, Halperin JL, Housholder-Hughes SD, Khan SS, Klarich K, Lin CH, Marine JE, McPherson JA, Niazi K, Ryan T, Solomon MA, Spicer RL, Tam M, Wang A, Weissman G, Weitz HH, Williams ES

2020 ACC/HFSA/ISHLT Lifelong Learning Statement for Advanced Heart Failure and Transplant Cardiology Specialists: A Report of the ACC Competency Management Committee.

Journal of the American College of Cardiology

Yancy CW, Drazner MH, Coffin ST, Cornwell W, Desai S, Erwin JP, Ginwalla M, Harshaw-Ellis KS, Horwich T, Kittleson M, Lala A, Lewsey SC, Marine JE, Martin CM, Meehan K, Morrow DA, Schlendorf K, Smith JW, Stevens GR

Small Left Ventricular Size Is an Independent Risk Factor for Ventricular Assist Device Thrombosis.

ASAIO journal (American Society for Artificial Internal Organs : 1992)

Chivukula VK, Beckman JA, Prisco AR, Lin S, Dardas TF, Cheng RK, Farris SD, Smith JW, Mokadam NA, Mahr C, Aliseda A

Left Ventricular Assist Device Inflow Cannula Angle and Thrombosis Risk.

Circulation. Heart failure

Chivukula VK, Beckman JA, Prisco AR, Dardas T, Lin S, Smith JW, Mokadam NA, Aliseda A, Mahr C

Invited Commentary.

The Annals of thoracic surgery

Smith JW, Mokadam NA

Pulmonary function tests do not predict mortality in patients undergoing continuous-flow left ventricular assist device implantation.

The Journal of thoracic and cardiovascular surgery

Bedzra EKS, Dardas TF, Cheng RK, Pal JD, Mahr C, Smith JW, Shively K, Masri SC, Levy WC, Mokadam NA

The Benefit of Donor-Recipient Matching for Patients Undergoing Heart Transplantation.

Journal of the American College of Cardiology

Nguyen VP, Mahr C, Mokadam NA, Pal J, Smith JW, Dardas TF

Outflow Graft Obstruction Treated With Transcatheter Management: A Novel Therapy for a New Diagnosis.

The Annals of thoracic surgery

Bhamidipati CM, Pal JD, Jones TK, McCabe JM, Reisman M, Smith JW, Mahr C, Mokadam NA

Successful Repair of Acute Type A Aortic Dissection 15 Years Following Bilateral Lung Transplantation.

Journal of cardiac surgery

Hermsen JL, Madathil R, Berfield KS, Li K, Smith JW, Mulligan MS

Endovascular Repair for Type A Aortic Dissection After Transcatheter Aortic Valve Replacement With a Medtronic CoreValve.

The Annals of thoracic surgery

Berfield KK, Sweet MP, McCabe JM, Reisman M, Mackensen GB, Mokadam NA, Dean LS, Smith JW

Systematic donor selection review process improves cardiac transplant volumes and outcomes.

The Journal of thoracic and cardiovascular surgery

Smith JW, O'Brien KD, Dardas T, Pal JD, Fishbein DP, Levy WC, Mahr C, Masri SC, Cheng RK, Stempien-Otero A, Mokadam NA

Periportal fibrosis without cirrhosis does not affect outcomes after continuous flow ventricular assist device implantation.

The Journal of thoracic and cardiovascular surgery

Sargent JE, Dardas TF, Smith JW, Pal JD, Cheng RK, Masri SC, Shively KR, Colyer LM, Mahr C, Mokadam NA

Late Surgical Bleeding Following Total Artificial Heart Implantation.

Journal of cardiac surgery

Hermsen JL, Smith JW, Pal JD, Mahr C, Masri SC, Dardas TF, Cheng RK, Mokadam NA

Self-administration education and polypharmacy in mechanical circulatory support patients.

The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Hermsen JL, Smith JW, Mokadam NA

The influence of (18)flourodeoxyglucose positron emission tomography on the management of gastroesophageal junction carcinoma.

American journal of surgery

Smith JW, Moreira J, Abood G, Aranha GV, Nagda S, Wagner RH, Shoup M

Immunologic responses to critical injury and sepsis.

Journal of intensive care medicine

Smith JW, Gamelli RL, Jones SB, Shankar R

New perspectives for a new century: implications of pathogen responses for the future of antimicrobial therapy.

Journal of burn care & research : official publication of the American Burn Association

Melstrom KA, Smith JW, Gamelli RL, Shankar R

Affiliation: